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Friday, July 24, 2020 | History

2 edition of Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity. found in the catalog.

Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity.

National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity.

by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

  • 35 Want to read
  • 28 Currently reading

Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English

    Subjects:
  • Carcinogens.,
  • Dyes and dyeing -- Toxicology.,
  • Phenylenediamine -- Toxicology.

  • Edition Notes

    SeriesCarcinogenesis technical report series ; no. 169, DHEW publication ; no. (NIH) 79-1725, DHEW publication -- no. (NIH) 79-1725.
    The Physical Object
    Pagination98 p. in various pagings :
    Number of Pages98
    ID Numbers
    Open LibraryOL18014051M

      Dominant lethal studies in rats of five hair dye components: 2-nitro-p-phenylenediamine, 4-nitro-o-phenylenediamine, m-phenylenediamine, 2,4-diaminoanisole sulfate, and 2,5-diaminoanisole sulfate. Toxicol. Appl. Pharmacol. 45, Google Scholar National Cancer Institute (b) Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity. Bethesda, MD. Public Health Service, National Institutes of Health, National Cancer Institute. (Carcinogenesis, Technical Report Series No ) [DHEW Publication No

      PubMed:Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity. PubMed: The mutagenic assay of some hair dye components, using the thymidine kinase locus of LY mouse lymphoma cells. PubMed: Testing of known carcinogens and noncarcinogens for their ability to induce unscheduled DNA synthesis in HeLa 1. Author(s): Litton-Bionetics, inc.; National Institutes of Health (U.S.); Carcinogenesis Testing Program (U.S.) Title(s): Bioassay of 4-nitro-o-phenylenediamine for

      Study population. The Copenhagen City Heart Study is a prospective study of the general population of Copenhagen, Denmark, initiated in – with follow-up examinations in –, –, –, and – [12,13].Participants aged 20 years and older were randomly selected from the general population using the Danish civil registration system []. Mutation Research, () Elsevier MTR Mutagenicity of selected aniline derivatives to Salmonella following plant activation and mammalian hepatic activation James M. Gentile 1, Glenda J. Gentile 1 and Michael J. Plewa 2 * Biology Department, Hope College, Holland, , and 2 Institute for Environmental Studies, University of Illinois, Urbana, IL (U.S.A


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Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

A bioassay for the possible carcinogenicity of 2-nitro-p-phenylenediamine was conducted using Fischer rats and B6C3F1 mice. 2-Nitro-p-phenylenediamine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each ://   A bioassay for the possible carcinogenicity of 2—nitro-p-phe­ nylenediamine was conducted using Fische 34r4 rats and B6C3F1 mice.

2-Nitro-p-phenylenediamine was administere idn the feed, at Get this from a library. Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity.

[National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.]   BIOASSAY OF 4-NITRO-o-PHENYLENEDIAMINE FOR POSSIBLE CARCINOGENICITY. CAS No. NCI-CG-TR U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE.

Public Health Service National Institutes of Health   2-Nitro-p-phenylenediamine: Target Organs and Levels of Evidence for TR Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity (CASRN ) Chemical (Study Title) Groups of 50 male and 50 female B6C3F1 mice were given 2-nitro-p-phenylenediamine in the feed at either or ppm for 78 wk.

Twenty animals of each sex were used as ent was followed by a 12–13 wk observation period. There was a dose-related depression of   A bioassay for the possible carcinogenicity of 2-nitro-p-phenylenediamine was conducted using Fischer rats and B6C3F1 mice.

2-Nitro-p-phenylenediamine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. Twenty animals of each sex and species were placed on test as :// A bioassay for the possible carcinogenicity of 4-nitro-o-phenylenediamine was conducted using Fischer rats and B6C3F1 mice.

4-Nitro-o-phenylenediamine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. Twenty animals of each sex and species were placed on test as ://   EPA has not classified p-phenylenediamine with respect to carcinogenicity.

Physical Properties The chemical formula for p-phenylenediamine is C6H8N2, and its molecular weight is g/mol. (2) p-Phenylenediamine occurs as a white to slightly red solid or crystals that darken on exposure to air; it is slightly soluble in water.

(2,4,7)   TR Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity (CAS No. ) "2-Nitro-p-phenylenediamine. a component of both semipermanent and permanent hair dye formulations, was selected for bioassay by the National Cancer Institute because of the increased incidence of bladder cancer among dye manufacturing industry a bioassay for possible carcinogenicity of 2-chloro-p-phenylenediamine sulfate was conducted using rats and mice.

the compound was administered in the feed, at either of 2 concentrations, to groups of male and female animals of each :// Myhr, B.C., and Caspary, W.J.

Evaluation of the LY mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics,  › Home › Chemical Effects in Biological Systems (CEBS). Bioassay of n-phenyl-p-phenylenediamine for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention. OCLC Number: Notes: "CAS no. " Description: Bioassay of 2-chloro-p-phenylenediamine sulfate for possible carcinogenicity (CAS No.

National Toxicology Program. Natl Cancer Inst Carcinog Tech Rep Ser,01 Jan Cited by: 0 articles | PMID: Applicant's summary and conclusion Conclusions: Sub-chronic toxicity tests were conducted with both rats and mice.

Rats were distributed among six groups, each consisting of five males and five females. 2-Nitro-p-phenylenediamine was incorporated into the basal laboratory diet and supplied ad libitum to five of the six rat groups in concentrations of,and mg/:// Carcinogenesis Technical Report Series No.

Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity. CAS No.NCI-CG-TR US Department of Health and Human Services, National Institutes of Health.

Wenninger, J. FDA's research and regulatory programs for cosmetics and :// A bioassay of N-phenyl-p-phenylenediamine for possible carcinogenicity was conducted by administering the test chemical in the diet to Fischer rats and B6C3F1 mice. Groups of 50 rats of each sex were administered /the test cmpd/ at one of two doses, either or 1, ppm, for 78 wk and were then observed for an additional 26 wk.

Matched 1. Author(s): Litton-Bionetics, inc.; National Institutes of Health (U.S.); Carcinogenesis Testing Program (U.S.) Title(s): Bioassay of 2-nitro-p-phenylenediamine for ().

Bioassay of 2-chloro-p-phenylenediamine sulfate for possiblecarcinogenicity. Bioassay of 2-nitro-p-phenylenediamine for possible carcinogenicity.

Bioassay of 2,4-dinitrotoluene for possible carcinogenicity. Bioassay of 2,6-dichloro-p-phenylenediamine for possible carcinogenicity.

Get this from a library. Bioassay of 4-chloro-o-phenylenediamine for possible carcinogenicity. [National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.]. A bioassay of 5-nitro-o-anisidine for possible carcinogenicity was conducted using Fischer rats and B6C3F1 mice.

/The cmpd/ was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each ://  Long-Term Carcinogenicity. 2-Year (Dosed-Feed) (C) Completed.

TR (NIH Number: ) (Peer Review Approval 08/31/A) Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity (CASRN ) Rats: F/N; Mice: B6C3F1; Carcinogenesis Results. Male Rats Negative ; Female Rats Negative ; Male Mice Negative2-Nitro-p-phenylenediamine (Cas No. ). Dietary administration of 2 -nitro- p -phenylenediamine was reported to be carcinogenic to female B6C3F 1 mice, causing an increased incidence of